Localized Thymic Amyloidosis Presenting with Myasthenia Gravis: Case Report
Journal of Korean Medical Science
;
: 145-148, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-200212
ABSTRACT
A mediastinal mass was incidentally found on chest radiography in a 46-yr-old woman who had had myasthenia gravis (MG) for 2 months. Computed tomography revealed a 4-cm in size, well-defined, and lobulating mass with nodular calcification that was located in the thymus. Microscopically, the mass consisted of diffuse amorphous eosinophilic materials. These deposits exhibited apple-green birefringence under polarized light microscopy after Congo red staining. Immunohistochemical analysis revealed that they were positive for both kappa and lambda light chains and negative for amyloid A. A diagnosis of localized primary thymic amyloidosis was finally made. After thymectomy, the symptoms of MG were controlled with reduced corticosteroid requirements. Localized thymic amyloidosis associated with MG has not been reported to date.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Timectomia
/
Timo
/
Calcinose
/
Radiografia Torácica
/
Tomografia Computadorizada por Raios X
/
Cadeias kappa de Imunoglobulina
/
Cadeias lambda de Imunoglobulina
/
Amiloidose
/
Mediastino
/
Miastenia Gravis
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2014
Tipo de documento:
Artigo
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