Factors affecting long-term survival after surgical resection of pancreatic ductal adenocarcinoma / 대한외과학회지
Journal of the Korean Surgical Society
;
: 394-401, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-200536
ABSTRACT
PURPOSE:
Some patients who undergo surgical resection of pancreatic cancer survive longer than other patients. The purpose of this study was to identify the factors that affect long-term survival after resection of histopathologically confirmed pancreatic ductal adenocarcinoma.METHODS:
A single-center, retrospective study was conducted among 164 patients who underwent surgical resection of pancreatic cancer, between May 1995 and December 2004. The patient follow-up process was conducted via telephone survey and review of electronic medical records for at least 5 years or until death.RESULTS:
We compared patients with long-term (> or =60 months, n = 19) and short-term survival (<60 months, n = 145). Resection margin status, differentiation of the tumor, tumor stage, pre-operative serum level of albumin, total bilirubin and carbohydrate antigen (CA) 19-9 level are related with survival difference (all factors, P < 0.05). Multivariate analysis revealed that a pre-operative serum total bilirubin level <7 mg/dL and a pre-operative serum CA19-9 level <37 U/mL is a statistically significant prognostic factor for long-term survival.CONCLUSION:
The preoperative serum total bilirubin and serum CA19-9 levels are associated with long-term survival after surgical resection of pancreatic cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ductos Pancreáticos
/
Neoplasias Pancreáticas
/
Telefone
/
Bilirrubina
/
Adenocarcinoma
/
Análise Multivariada
/
Estudos Retrospectivos
/
Seguimentos
/
Registros Eletrônicos de Saúde
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of the Korean Surgical Society
Ano de publicação:
2011
Tipo de documento:
Artigo
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