Photochemotherapy-induced Lentigines on a Vitiliginous Patch Electron Microscopic Observations
Yonsei Medical Journal
;
: 66-71, 1988.
Artigo
em Inglês
| WPRIM
| ID: wpr-20075
ABSTRACT
Patients with vitiligo seem be less prone to the development of lentigines as a side effect of long-term photochemotherapy than do psoriatics. An 8-year-old boy who had a vitiliginous patch on his left thigh, had been receiving photochemotherapy since he was 2 years old. At the age of 3, multiple star-shaped brownish macules developed at the site of treatment. Photochemotherapy was continued until the patient was 6 year old, at which time no improvement in the vitiligo was seen, so photochemotherapy was discontinued. Now 2 years after treatment the lentigines still persist. On electron microscopic examination, the melanocytes showed two patterns of cell death coagulative necrosis and apotosis together with atypical cytoplasmic and melanosomal alterations.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Terapia PUVA
/
Vitiligo
/
Microscopia Eletrônica
/
Lentigo
/
Melanócitos
Limite:
Criança
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Yonsei Medical Journal
Ano de publicação:
1988
Tipo de documento:
Artigo
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