The expression and cellular localization of phospholipase D isozymes in the developing mouse testis
Journal of Veterinary Science
;
: 209-212, 2007.
Artigo
em Inglês
| WPRIM
| ID: wpr-200811
ABSTRACT
To examine the involvement of phospholipase D (PLD)isozymes in postnatal testis development, the expression ofPLD1 and PLD2 was examined in the mouse testis atpostnatal weeks 1, 2, 4, and 8 using Western blot analysisand immunohistochemistry. The expression of both PLD1and PLD2 increased gradually with development frompostnatal week 1 to 8. Immunohistochemically, PLDimmunoreactivity was detected in some germ cells in thetestis and interstitial Leydig cells at postnatal week 1.PLD was mainly detected in the spermatocytes andresidual bodies of spermatids in the testis after 8 weeksafter birth. The intense immunostaining of PLD in Leydigcells remained unchanged by postnatal week 8. Thesefindings suggest that PLD isozymes are involved in thespermatogenesis of the mouse testis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fosfolipase D
/
Espermatogênese
/
Testículo
/
Imuno-Histoquímica
/
Western Blotting
/
Isoenzimas
/
Camundongos Endogâmicos BALB C
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2007
Tipo de documento:
Artigo
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