Seroprevalence of Hepatitis A and Associated Socioeconomic Factors in Young Healthy Korean Adults
Gut and Liver
;
: 88-92, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-201092
ABSTRACT
BACKGROUND/AIMS:
An epidemiologic shift of hepatitis A virus (HAV) seroprevalence is expected due to an improvement in socioeconomic status in young adults in Korea. We investigated the age-specific seroprevalence and socioeconomic factors associated with HAV seropositivity in young, healthy Korean adults.METHODS:
Between March 2009 and February 2010, a total of 5,051 persons from 20 to 49 years of age presenting for a health check-up were included and responded to a questionaire. The seroprevalence of HAV was investigated by measuring immunoglobulin G (IgG) anti-HAV. A total of 984 pairs of cases and age- and sex-matched controls were analyzed for associated socioeconomic factors.RESULTS:
The prevalence of seropositive HAV was 6.2% in the 20 to 29 age range, 33.1% in the 30 to 39 range and 82.4% in the 40 to 49 range (p<0.001). There were no significant differences in any group according to gender. A multivariate analysis for paired cases indicated that HAV seropositivity was significantly higher in the low monthly income (below five million won, approximately 4,300 dollars) group and the Helicobacter pylori (H. pylori)-positive group (odds ratio [OR], 1.65; 95% confidence interval [CI], 1.27-2.14; p<0.001; OR, 1.45; 95% CI, 1.19-1.76; p<0.001, respectively).CONCLUSIONS:
HAV seropositivity in young adults presenting for a health checkup appears to be decreasing, and the prevalence was significantly higher in the low monthly income group and the H. pylori-positive group.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Classe Social
/
Fatores Socioeconômicos
/
Imunoglobulina G
/
Estudos Soroepidemiológicos
/
Prevalência
/
Análise Multivariada
/
Helicobacter pylori
/
Vírus da Hepatite A
/
Anticorpos Anti-Hepatite A
/
Hepatite
Tipo de estudo:
Estudo de prevalência
Limite:
Adulto
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Gut and Liver
Ano de publicação:
2011
Tipo de documento:
Artigo
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