Intravitreal Bevacizumab Injection in Adult Coats' Disease
Journal of the Korean Ophthalmological Society
;
: 630-634, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-201701
ABSTRACT
PURPOSE:
To report the efficacy of intravitreal bevacizumab injection in adult patients with Coats' disease. CASESUMMARY:
Vascular telangiectasia, microaneurysms, circinate hard exudates, and macular edema were shown in the macula of two patients. Vascular abnormality was limited to < or =6 clock hours in both cases. In case 1, the temporal retina demonstrates filigree-like vessels and capillary nonperfusion. In case 2, the nasal retina demonstrates aneurysmal dilatation and multiple microaneurysms. Intravitreal bevacizumab injection was administered in both cases. After 1 month, macular edema decreased. Laser photocoagulation was performed for vascular telangiectasia, microaneurysms, and capillary nonperfusion area. Then an additional decrease of macular edema was observed. Fluorescein leakage decreased, as well. After 1 month (case 1) and 2 months (case 2), macular edema increased. The second and third intravitreal reinjections were administered to each patient. Macular edema decreased.CONCLUSIONS:
We report two rare cases of Coats' disease in adult patients. Intravitreal bevacizumab injection in patients with Coats' disease can result in a rapid decrease of macular edema, which will then lead to rapid visual recovery and an opportunity for effective laser photocoagulation. We recommend that intraviteal bevacizumab injection be used in combination with laser photocoagulation for the treatment of Coats' disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Retina
/
Telangiectasia
/
Capilares
/
Edema Macular
/
Fluoresceína
/
Dilatação
/
Exsudatos e Transudatos
/
Anticorpos Monoclonais Humanizados
/
Bevacizumab
/
Aneurisma
Limite:
Adulto
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2009
Tipo de documento:
Artigo
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