Performance of a low cost magnifying device, magnivisualizer, versus colposcope for detection of pre-cancer and cancerous lesions of uterine cervix / 부인종양
Journal of Gynecologic Oncology
; : 282-286, 2014.
Article
em En
| WPRIM
| ID: wpr-202143
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE: To assess the performance of a low cost magnifying device (Magnivisualizer) compared to a standard optical colposcope for detection of precancerous and cancerous lesions of the uterine cervix. METHODS: A total of 659 consecutive symptomatic women attending a gynecologic outpatient clinic underwent unaided visual inspection followed by cytology, visual inspection of the cervix using 5% acetic acid (VIA), and VIA under magnification (VIAM) with the Magnivisualizer. All women, independently of test results, were referred for colposcopic examination. Colposcopic-directed biopsies were obtained from all positive lesions and compared to positive VIAM cases. RESULTS: The detection rate for VIA positive lesions was 12% (134/659), while it was 29% for VIAM positive lesions (191/659). The sensitivities of detection of cervical intraepithelial neoplasia (CIN) 2 and higher lesions were 61.7% for VIA, 88.3% for VIAM, and 86.7% for colposcopy, with a specificity of 58.5% for VIA, 55.8% for VIAM, and 90.4% for colposcopy. The performance of colposcopy and VIAM was moderate (kappa, 0.48; 95% confidence interval [CI], 0.41 to 0.54) for detection of CIN 1 and higher lesions and excellent (kappa, 0.87; 95% CI, 0.82 to 0.94) for detection of CIN 2 and higher lesions. CONCLUSION: In low resource settings, where colposcopic facilities are not available at the community level, a simple low-cost, handheld Magnivisualizer can be considered a valid option for detection of cervical precancerous and cancerous lesions. However, it cannot replace traditional colposcopy because it has a low specificity that results in many unnecessary biopsies.
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Texto completo:
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Índice:
WPRIM
Assunto principal:
Ambulatório Hospitalar
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Biópsia
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Displasia do Colo do Útero
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Neoplasias do Colo do Útero
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Reprodutibilidade dos Testes
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Colposcopia
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Ácido Acético
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Colposcópios
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Desenho de Equipamento
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Detecção Precoce de Câncer
Tipo de estudo:
Diagnostic_studies
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Health_economic_evaluation
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Screening_studies
Limite:
Adult
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Aged
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Female
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Humans
Idioma:
En
Revista:
Journal of Gynecologic Oncology
Ano de publicação:
2014
Tipo de documento:
Article