Developmental Changes of Membrane Proteins from Human Erythrocytes
Journal of the Korean Pediatric Society
;
: 541-546, 1982.
Artigo
em Coreano
| WPRIM
| ID: wpr-202515
ABSTRACT
To investigate the developmental changes of human erythrocytes, adult and fetal erythrocyte membranes prepared from adult and cord blood were analyzed in regard to their proteins, glycoproteins, enzyme activities and glucose transport systems. 1. Adult and fetal erythrocyte membranes appeared to have the same major proteins and gl-ycoproteins in the electrophoretic pattern. 2. ATPase activity in adult erythrocyte membranes was lower than that of fetal erythrocyte membranes, whereas adult cholinesterase was higher. No significant change was observed in the activities of alkaline and acid phosphatases during development. 3. Glucose uptake was higher in fetal erythrocytes than in adult erythrocytes, suggesting some loss of glucose carrier system during devlopment. The results suggest that the major structural proteins in human erythrocyte membrane relatively unchanged while some functional proteins such as membrane enzymes and carrier proteins in transport systems are markedly changed during development.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Glicoproteínas
/
Proteínas de Transporte
/
Colinesterases
/
Adenosina Trifosfatases
/
Monoéster Fosfórico Hidrolases
/
Membrana Eritrocítica
/
Eritrócitos
/
Sangue Fetal
/
Glucose
/
Proteínas de Membrana
Limite:
Adulto
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Pediatric Society
Ano de publicação:
1982
Tipo de documento:
Artigo
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