Your browser doesn't support javascript.
loading
Shear Wave Elastography for Detection of Prostate Cancer: A Preliminary Study
Korean Journal of Radiology ; : 346-355, 2014.
Artigo em Inglês | WPRIM | ID: wpr-203185
ABSTRACT

OBJECTIVE:

To assess the diagnostic value of shear wave elastography (SWE) for prostate cancer detection. MATERIALS AND

METHODS:

In this retrospective study, 87 patients with the suspicion of prostate cancer (prostate-specific antigen > 4 ng/mL and abnormal digital rectal examination) underwent a protocol-based systematic 12-core biopsy followed by targeted biopsy at hypoechoic areas on grey-scale ultrasound. Prior to biopsy, SWE was performed by placing two circular 5 mm-sized regions of interest (ROIs) along the estimated biopsy tract in each sector and one ROI for hypoechoic lesions. SWE parameters, S (mean stiffness) and R (mean stiffness ratio), were calculated and compared regarding different histopathologic tissues and their accuracy for diagnosing prostate cancer was analyzed. SWE parameters were correlated with Gleason score and were compared between indolent ( or = 8) tissues in prostate cancer patients.

RESULTS:

Prostate cancer was detected in 7.5% of 1058 cores in 29.9% of 87 patients. Seven (43.8%) of 16 hypoechoic lesions were confirmed as prostate cancer. SWE parameters were significantly different among the histopathologic entities (p 43.9 kPa and 60.8%, 66.4%, and 0.653, respectively, for R > 3. Both, S and R showed a significant correlation with Gleason score (r > or = 0.296, p < or = 0.008) and were significantly different between indolent and aggressive prostate cancer (p < or = 0.006).

CONCLUSION:

Shear wave elastographic parameters are significantly different between prostate cancer and benign prostate tissue and correlate with Gleason score.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Próstata / Neoplasias da Próstata / Biópsia / Estudos Retrospectivos / Curva ROC / Sensibilidade e Especificidade / Antígeno Prostático Específico / Ultrassonografia de Intervenção / Técnicas de Imagem por Elasticidade / Gradação de Tumores Tipo de estudo: Estudo diagnóstico / Guia de Prática Clínica / Estudo observacional / Estudo prognóstico Limite: Adulto / Idoso / Aged80 / Humanos / Masculino Idioma: Inglês Revista: Korean Journal of Radiology Ano de publicação: 2014 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Próstata / Neoplasias da Próstata / Biópsia / Estudos Retrospectivos / Curva ROC / Sensibilidade e Especificidade / Antígeno Prostático Específico / Ultrassonografia de Intervenção / Técnicas de Imagem por Elasticidade / Gradação de Tumores Tipo de estudo: Estudo diagnóstico / Guia de Prática Clínica / Estudo observacional / Estudo prognóstico Limite: Adulto / Idoso / Aged80 / Humanos / Masculino Idioma: Inglês Revista: Korean Journal of Radiology Ano de publicação: 2014 Tipo de documento: Artigo