Results of Combined Chemotherapy and Radiotherapy for Advanced Intraocular Retinoblastoma
Journal of the Korean Ophthalmological Society
;
: 1528-1537, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-20360
ABSTRACT
PURPOSE:
To report the result of combined chemotherapy and radiotherapy for 5 retinoblastoma patients.METHODS:
Retrospective study of 5 patients (8 eyes) who were diagnosed with retinoblastoma of group III to V in the Reese-Ellsworth (R-E) classification was done. After 6 cycles of chemotherapy consisting of Vincristine, VP-16 (Etoposide) and Carboplatin, Radiotherapy (4500Gy/5weeks) was done. Neoaedjuvant therapy consisting of Nimustine and Carboplatin was done, and supplementary laser photocoagulation was done in 1 case. Mean follow-up period is 33 months.RESULTS:
Significant reduction of tumor size and regression were observed in five eyes of R-E classification group V, and slight reduction of tumor size and regression were observed in three eyes of R-E classification groups III and IV. There was no recurrence and no new mass was detected.CONCLUSIONS:
Combined chemotherapy, radiotherapy and supplementary therapy may save eyeballs which were diagnosed with retinoblastoma, even R-E classification group V.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Radioterapia
/
Recidiva
/
Retinoblastoma
/
Vincristina
/
Nimustina
/
Estudos Retrospectivos
/
Seguimentos
/
Carboplatina
/
Classificação
/
Tratamento Farmacológico
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2003
Tipo de documento:
Artigo
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