Evaluation of Patients with Rheumatoid Arthritis by Tc-99m MIBI Imaging / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 506-510, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-203798
ABSTRACT
PURPOSE:
We investigated whether Tc-99m MIBI imaging is useful to predict the response of drug treatment in patients with rheumatoid arthritis. MATERIALS ANDMETHODS:
24 patients (15 women and 9 men, age 49 +/- 12 year) rheumatoid arthritis and treated with disease modifying antirheumatic drugs (DMARDs) were included in this study. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were measured, and Tc-99m MIBI scan was obtained before drug treatment. Quantitative analysis of uptake in diseased joints was performed and expressed as joint-to background ratio (J/B) and percent retention (%R) of Tc-99m MIBI. Clinical symptoms were evaluated and graded from 0 (no) to 3 (severe) regarding to presence of tenderness and swelling.RESULTS:
J/B of the diseased joints were significantly correlated with ESR and CRP (p< 0.05). A highly significant correlation was found between the improvement of clinical symptoms and %R of Tc-99m MIBI (p< 0.05).CONCLUSION:
The results demonstrate that Tc-99m MIBI scan may be used to predict the therapeutic response in patients with rheumatoid arthritis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artrite Reumatoide
/
Sedimentação Sanguínea
/
Proteína C-Reativa
/
Antirreumáticos
/
Articulações
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Nuclear Medicine
Ano de publicação:
2004
Tipo de documento:
Artigo
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