Two Cases of Generalized Pustular Psoriasis Improved with Combination Treatment of Mycophenolate Mofetil / 대한피부과학회지
Korean Journal of Dermatology
; : 1644-1649, 2003.
Article
em Ko
| WPRIM
| ID: wpr-203956
Biblioteca responsável:
WPRO
ABSTRACT
Mycophenolate mofetil(MMF) is a new immunosuppressant which non-competitively and reversibly blocks the de novo synthesis of guanine nucleotides required for DNA and RNA synthesis during lymphocyte proliferation. So MMF selectively inhibits lymphocyte proliferation and it has less side-effects than other immunosuppressants. We described 2 cases of generalized pustular psoriasis improved with MMF. We administered MMF combined with cyclosporin in case 1 and acitretin in case 2. Both patients markedly improved with MMF administration 3 days after and had no severe side-effects. Thus the authors thought that MMF appears to be an effective therapeutic alternative in the treatment of generalized pustular psoriasis.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Psoríase
/
DNA
/
RNA
/
Linfócitos
/
Ciclosporina
/
Acitretina
/
Nucleotídeos de Guanina
/
Imunossupressores
Limite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Dermatology
Ano de publicação:
2003
Tipo de documento:
Article