The Effects of Muscle Relaxants and Intravenous Anesthetics on Intraocular Pressure / 대한마취과학회지

ABSTRACT

The effects of muscle relaxants and intravenous anesthetics on intraocular pressure(IOP) were studied in 40 patients ranging in age from 12~63 years and undergoning elective non-ophthalmic surgery. IOP was measured with the PErkins Applanation Tonometer before induction, 1 minute and 2 minutes after intravenous anesthesia, 1 minute after succinylcholine and 1 minute after intubation. The patients were divided into 4 groups thiopental+succinylcholine+intubation (group A, control group) pnacuronium pretreatment+thiopental+succinylcholine+intubation (group B) ketamine+succinylcholine+intubation (group C) and, pancuronium+ketamine+succinylcholine+intubation(group D). The results were as follows 1) In group A, IOP changes following thiopental (5mg/kg) administration showed a highly significant decrease (p0.05). 3)IOP changes after 1 minute following succinylcholine(1mg/kg) administration showed significant increases(p<0.05) in group A, C and highly significant increases(p<0.01) in group D. IOP changes after 1 minute of endotracheal intubation showed highly significant increases (p<0.01) compared with the control value in group A, C and D. 4) Pretreatment with a mondepolarizing muscle reaxant could not prevent the increase in IOP following succinylcholine administration.