Febrile Urinary Tract Infections Caused by Community-Acquired Extended-Spectrum beta-Lactamase-Producing and-Nonproducing Bacteria: A Comparative Study
Pediatric Infection & Vaccine
; : 29-35, 2015.
Article
em Ko
| WPRIM
| ID: wpr-204527
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: The purpose of this study was to investigate the clinical characteristics and outcome of febrile urinary tract infections (UTIs) caused by community-acquired extended-spectrum beta-lactamase (CA-ESBL)-producing and -nonproducing bacteria. METHODS: We analyzed febrile UTIs in children hospitalized at Gachon University Gil Medical Center from January 2011 to December 2013 through retrospective data collection from their medical records. RESULTS: Among pathogens causing 374 episodes of UTIs, the proportion of ESBL-producing bacteria was 13.1% (49/374). The proportion of ESBL-producing Escherichia coli and Klebsiella spp. was 13.6% (48/354) and 5.0% (1/20), respectively. There was no significant difference between the CA-ESBL and CA non-ESBL groups in duration of fever (4.2+/-2.7 vs.3.7+/-2.1 days, P=0.10) and bacterial eradication rate with empirical antibiotics (100% vs. 100%). The risk of cortical defects on renal scan significantly depended on existence of vesicoureteral reflux rather than ESBL production of pathogen. CONCLUSIONS: There was no significant difference between the CA-ESBL and CA non-ESBL groups in renal cortical defects and clinical outcome. Careful choice of antibiotics is important for treatment of community-acquired UTI in children.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Bactérias
/
Infecções Urinárias
/
Refluxo Vesicoureteral
/
Beta-Lactamases
/
Prontuários Médicos
/
Coleta de Dados
/
Estudos Retrospectivos
/
Escherichia coli
/
Febre
/
Klebsiella
Tipo de estudo:
Observational_studies
Limite:
Child
/
Humans
Idioma:
Ko
Revista:
Pediatric Infection & Vaccine
Ano de publicação:
2015
Tipo de documento:
Article