Quinolone susceptibility and genetic characterization of Salmonella enterica subsp. enterica isolated from pet turtles / 한국실험동물학회지
Laboratory Animal Research
;
: 49-56, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-204562
ABSTRACT
Turtle-borne Salmonella enterica owns significance as a leading cause in human salmonellosis. The current study aimed to determine the quinolone susceptibility and the genetic characteristics of 21 strains of S. enterica subsp. enterica isolated from pet turtles. Susceptibility of four antimicrobials including nalidixic acid, ciprofloxacin, ofloxacin, and levofloxacin was examined in disk diffusion and MIC tests where the majority of the isolates were susceptible to all tested quinolones. In genetic characterization, none of the isolates were positive for qnr or aac(6')-Ib genes and no any target site mutations could be detected in gyrA, gyrB, and parC quinolone resistance determining regions (QRDR). In addition, neighbor-joining phylogenetic tree derived using gyrA gene sequences exhibited two distinct clads comprising; first, current study isolates, and second, quinolone-resistant isolates of human and animal origin. All results suggest that studied strains of S. enterica subsp. enterica isolated from pet turtles are susceptible to quinolones and genetically more conserved with regards to gyrA gene region.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Salmonella
/
Infecções por Salmonella
/
Árvores
/
Tartarugas
/
Ofloxacino
/
Ciprofloxacina
/
Ácido Nalidíxico
/
Quinolonas
/
Salmonella enterica
/
Difusão
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Laboratory Animal Research
Ano de publicação:
2017
Tipo de documento:
Artigo
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