Inherited Vitamin K Deficiency: Case Report and Review of Literature
Yonsei Medical Journal
;
: 923-927, 2003.
Artigo
em Inglês
| WPRIM
| ID: wpr-205353
ABSTRACT
Vitamin K is the cofactor for the hepatic carboxylation of glutamic acid residues in a number of proteins including the procoagulants factors ll, Vll, lX, and X. The role of vitamin K in normal bone function is not fully understood. Inherited deficiency of vitamin K dependent coagulation factors is a rare bleeding disorder reported only in a few patients. Here we present an 18-month old child who presented with osteopeni due to inherited vitamin K deficiency. While the patient had high bone specific alkaline phosphatase and parathyroid hormone levels and low osteocalcin and bone mineral density values, with the regular supplementation of vitamin K all the mentioned parameters returned to normal values.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tempo de Protrombina
/
Deficiência de Vitamina K
/
Doenças Ósseas Metabólicas
/
Densidade Óssea
/
Osteocalcina
Limite:
Humanos
/
Lactente
/
Masculino
Idioma:
Inglês
Revista:
Yonsei Medical Journal
Ano de publicação:
2003
Tipo de documento:
Artigo
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