Factors Associated with Airway Disease and Interstitial Lung Disease in Rheumatoid Arthritis
Journal of Rheumatic Diseases
;
: 101-108, 2016.
Artigo
em Coreano
| WPRIM
| ID: wpr-205475
ABSTRACT
OBJECTIVE:
This study examined lung involvement in patients with rheumatoid arthritis (RA) and identified factors associated with airway disease (AD) and interstitial lung disease (ILD).METHODS:
A total of 507 RA patients were enrolled in a cross-sectional study. Lung involvement was assessed by high-resolution computed tomography scan. The patient groups were classified according to normal, AD, and ILD. Multinomial logistic regression analysis was performed to identify factors associated with AD and ILD.RESULTS:
The most frequent lung involvement was AD (38.3%) followed by ILD (12.6%). Old age (adjust odds ratio [aOR] 2.58, 95% confidence interval [CI] 1.70 to 3.90 for AD; aOR 4.38, 95% CI 2.30 to 8.35 for ILD), male gender (aOR 2.57, 95% CI 1.22 to 5.42 for AD; aOR 5.48, 95% CI 2.20 to 13.65 for ILD) were factors associated with AD and ILD in RA patients. ILD was associated with short disease duration (aOR 0.30, 95% CI 0.14 to 0.62), AD was associated with high titers of anti-cyclic citrullinated peptides antibodies (anti-CCP; aOR 1.61, 95% CI 1.07 to 2.44).CONCLUSION:
AD was the most frequent lung involvement in patients with RA. Old age and male gender were both associated with AD and ILD. Short disease duration was associated with ILD. High titers of anti-CCP was associated with AD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peptídeos
/
Artrite Reumatoide
/
Tomografia Computadorizada por Raios X
/
Modelos Logísticos
/
Razão de Chances
/
Estudos Transversais
/
Fatores de Risco
/
Doenças Pulmonares Intersticiais
/
Pulmão
/
Pneumopatias Obstrutivas
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2016
Tipo de documento:
Artigo
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