Endoscopic Closure for Full-Thickness Gastrointestinal Defects: Available Applications and Emerging Innovations
Clinical Endoscopy
;
: 438-443, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-205870
ABSTRACT
Full-thickness gastrointestinal defects such as perforation, anastomotic leak, and fistula are severe conditions caused by various types of pathologies. They are more likely to require intensive care and a long hospital stay and have high rates of morbidity and mortality. After intentional full-thickness opening of hollow organs for natural orifice transluminal endoscopic surgery, safe and secure closure is urgently required. The currently available advanced endoscopic closing techniques have a major role in the treatment of full-thickness gastrointestinal defects. Appropriate usage of these techniques requires taking into account their advantages and limitations during practical application. We reviewed the available endoscopic modalities, including endoscopic clips, stents, vacuum-assisted closure, gap filling, and suturing devices, discussed their advantages and limitations when treating full-thickness gastrointestinal defects, and explored emerging innovations, including a novel endoluminal surgical platform for versatile suturing and a cell-laden scaffold for effective gap filling. Although these emerging technologies still require further pre-clinical and clinical trials to assess their feasibility and efficacy, the available modalities may be replaced and refined by these new techniques in the near future.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Stents
/
Mortalidade
/
Cuidados Críticos
/
Tratamento de Ferimentos com Pressão Negativa
/
Fístula Anastomótica
/
Cirurgia Endoscópica por Orifício Natural
/
Fístula
/
Tempo de Internação
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Clinical Endoscopy
Ano de publicação:
2016
Tipo de documento:
Artigo
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