Metastatic Leiomyosarcoma of the Pancreas Mimicking a Cystic Neoplasm: A Case Report

ABSTRACT

Pancreatic tumors are primary in most cases. Pancreatic metastases associated with other primary malignancies, especially pancreatic metastasis of leiomyosarcoma, are infrequent. A 49-year-old woman underwent surgical resection of a mass in the right groin, which was diagnosed as a leiomyosarcoma and she was well for 4 years without evidence of disease recurrence. As part of her routine follow-up, an abdominal computed tomography (CT) identified a cystic neoplasm of the pancreas. Pylorus-preserving pancreaticoduodenectomy was performed. Microscopically, the tumor was composed of spindle cells with a predominantly fascicular pattern, which was consistent with a leiomyosarcoma that was metastatic to the pancreas. We report here a unique case of pancreatic metastasis from a leiomyosarcoma, which was resectable and mimicked a primary cystic neoplasm.