Imatinib-induced Psoriasiform Drug Eruption in a Patient with a Gastrointestinal Stromal Tumor / 대한피부과학회지
Korean Journal of Dermatology
;
: 388-391, 2015.
Artigo
em Coreano
| WPRIM
| ID: wpr-206793
ABSTRACT
Imatinib mesylate (Gleevec(R)) is a small-molecule inhibitor that selectively inhibits the tyrosine kinase family, including mutated KIT oncoproteins in gastrointestinal stromal tumors (GIST). However, cutaneous reactions to imatinib are common and occur in 7.0% to 88.9% of patients. Nonspecific skin rashes, facial edema, and pruritus are the most common adverse reactions. However, development of psoriasiform drug eruption owing to the drug has rarely been reported. Herein we report on a 66-year-old male patient with GIST who had taken imatinib (400 mg/day) for 2 months. He developed erythematous scaly macules and papules on the trunk and extremities. Histopathological findings were compatible with a psoriasiform drug eruption.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prurido
/
Psoríase
/
Proteínas Tirosina Quinases
/
Proteínas Oncogênicas
/
Toxidermias
/
Mesilatos
/
Tumores do Estroma Gastrointestinal
/
Edema
/
Exantema
/
Extremidades
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
2015
Tipo de documento:
Artigo
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