A case of central pontine myelinolysis in uremic patient with peritoneal dialysis / 대한내과학회지

ABSTRACT

Central pontine myelinolysis (CPM) is a rare syndrome, especially in uremic patients undergoing dialysis. CPM induced by diabetic coma in hemodialysis patients or associated with rapid correction of hyponatremia in peritoneal dialysis patients have been reported. However, its pathogenesis has been unclear. We report a case of CPM in a 67-year-old female uremic patient undergoing continuous ambulatory peritoneal dialysis, who was admitted to our hospital for drowsy mentality. Sodium was normal (140 mEq/L) initially and throughout the entire clinical course. The fasting blood sugar level was 110 mg/dL, serum osmolality 312 mOsm/KgH2O and osmolar gap 9.47. The axial T2-weighted brain MRI showed high signal intensity in the basal pons.