Low-dose, Whole-lung Radiotherapy for Pulmonary Extramedullary Hematompoiesis : A case report

ABSTRACT

A seventy-seven year old female was consulted for radiation therapy due to the infiltration of lung and pleural effusion from myelofibrosis. She was diagnosed clinically as extramedullary hematopoiesis (EMH), and had severe dyspnea and cardiac dysfunction originated from pulmonary hypertension. She underwent low-dose (2 Gy) whole-lung radiation therapy in 4fractions of 50 cGy each. Clinical symptom, especially dyspnea, and chest X-ray imaging was markedly improved after radiation therapy. We experienced that the low-dose whole-lung radiation therapy to EMH in lung might be effective for the palliation of pulmonary hypertension