Radiotherapy of Brain Metastases from Lung Cancer
Journal of Lung Cancer
;
: 34-37, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-207842
ABSTRACT
PURPOSE:
Brain metastasis is estimated to occur in 10~45% of solid cancer patients, and is the most common intracranial tumor in adults. Several neurologic symptom palliations are made with steroid therapy and whole brain irradiation. MATERIALS ANDMETHODS:
We evaluated respectively the clinical characteristics and treatment outcome for 44 patients with metastatic brain tumor from lung cancer during the period from April 2000 to December 2003.RESULTS:
Median age of the patients was 61 years. The male female ratio was 2.7 1. Synchronous and metachronous brain metastasis was seen in 18 (40.9%) and 26 patients (59.1%), respectively and median duration between the diagnosis of lung cancer and brain metastases was 6 months (range 1~18 months) in metachronous cases. Pathologic types of lung cancer were as follows small cell lung cancer in 11 patients and non-small cell lung cancer in 33 patients (squamous cell carcinoma-13, adenocarcinoma-11, large cell carcinoma- 3, others-6). The most common symptom of brain metastasis was headache, which was in 27 patients (61.4%). Seven patients (15.9%) had a single brain metastasis while 37 patients (84.1%) had multiple brain metastases. The total radiation dose to whole brain ranged from 30 to 40 Gy (median 30 Gy). In 29 patients (65.9%) neurological symptoms were resolved after whole brain irradiation. Median survival was 18 weeks for patients with steroid therapy and whole brain radiotherapy.CONCLUSION:
In present study, we confirmed that whole brain irradiation is an effective palliative treatment for patients with metastatic brain tumors from lung cancer
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cuidados Paliativos
/
Radioterapia
/
Encéfalo
/
Neoplasias Encefálicas
/
Resultado do Tratamento
/
Carcinoma Pulmonar de Células não Pequenas
/
Diagnóstico
/
Carcinoma de Pequenas Células do Pulmão
/
Cefaleia
/
Pulmão
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of Lung Cancer
Ano de publicação:
2005
Tipo de documento:
Artigo
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