Serum interferon-gamma and interleukins-6 and -8 during infection with Fasciola gigantica in cattle and buffaloes
Journal of Veterinary Science
;
: 135-139, 2005.
Artigo
em Inglês
| WPRIM
| ID: wpr-207855
ABSTRACT
This study investigated the presence of cytokines interferon (IFN)-gamma, interleukins (IL) -6 and -8 in serum of cattle and buffaloes infected with Fasciola gigantica from one to 16 weeks post-infection to determine their T cell response during infection. The concentration of these cytokines was determined by sandwich enzyme-linked immunosorbent assay (ELISA). No IFN-gamma was detected in these animals while IL-6 was elevated from one to 16 weeks postinfection. Levels of IL-8 were also elevated in infected buffaloes from one to 16 weeks post-infection. A predominantly T helper (Th) 2 response which started early in the infection was apparently present in cattle and buffaloes in this study which was characterised by IL-6. IL-8 production could be another mechanism of immune response in buffaloes during infection with F. gigantica.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Búfalos
/
Ensaio de Imunoadsorção Enzimática
/
Distribuição Aleatória
/
Doenças dos Bovinos
/
Citocinas
/
Interleucina-8
/
Interleucina-6
/
Interferon gama
/
Fasciola
/
Fasciolíase
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2005
Tipo de documento:
Artigo
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