Bone Positron Emission Tomography with or without CT Is More Accurate than Bone Scan for Detection of Bone Metastasis
Korean Journal of Radiology
;
: 510-519, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-208254
ABSTRACT
OBJECTIVE:
Na18F bone positron emission tomography (bone PET) is a new imaging modality which is useful for the evaluation of bone diseases. Here, we compared the diagnostic accuracies between bone PET and bone scan for the detection of bone metastasis (BM). MATERIALS ANDMETHODS:
Sixteen cancer patients (MF = 106, mean age = 60 +/- 12 years) who underwent both bone PET and bone scan were analyzed. Bone PET was conducted 30 minutes after the injection of 370 MBq Na18F, and a bone scan was performed 3 hours after the injection of 1295 MBq 99mTc-hydroxymethylene diphosphonate.RESULTS:
In the patient-based analysis (8 patients with BM and 8 without BM), the sensitivities of bone PET (100% = 8/8) and bone scan (87.5% = 7/8) were not significantly different (p > 0.05), whereas the specificity of bone PET (87.5% = 7/8) was significantly greater than that of the bone scan (25% = 2/8) (p < 0.05). In the lesion-based analysis (43 lesions in 14 patients; 31 malignant and 12 benign), the sensitivity of bone PET (100% = 31/31) was significantly greater than that of bone scan (38.7% = 12/31) (p < 0.01), and the specificity of bone PET (75.0% = 9/12) was also significantly higher than that of bone scan (8.3% = 1/12) (p < 0.05). The receiver operating characteristic curve analysis showed that bone PET was significantly more accurate than the bone scan in the patient (p = 0.0306) and lesion (p = 0.0001) based analyses.CONCLUSION:
Na18F bone PET is more accurate than bone scan for BM evaluation.
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Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sódio
/
Neoplasias Ósseas
/
Radioisótopos de Flúor
/
Tomografia Computadorizada por Raios X
/
Compostos de Organotecnécio
/
Estudos Retrospectivos
/
Sensibilidade e Especificidade
/
Área Sob a Curva
/
Fluordesoxiglucose F18
/
Tomografia por Emissão de Pósitrons
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Korean Journal of Radiology
Ano de publicação:
2013
Tipo de documento:
Artigo
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