Comparison of Clinicopathologic and Immunohistochemical Features between Localized and Diffuse Types of Tenosynovial Giant Cell Tumor / 대한정형외과연구학회지
Journal of Korean Orthopaedic Research Society
;
: 40-47, 2013.
Artigo
em Coreano
| WPRIM
| ID: wpr-208510
ABSTRACT
PURPOSE:
Tenosynovial giant cell tumors (TSGCT) can be classified into localized and diffuse types. To identify reliable diagnostic markers for these tumors, we compared clinicopathologic and immunohistochemical features in localized and diffuse type TSGCT. MATERIALS ANDMETHODS:
Clinicopathologic and immunohistochemical studies were perfomed. Thirty cases which had been histologically diagnosed as TSGCT after surgery, at our hospital from 2000 to 2012, were analyzed.RESULTS:
There was no statistically significant difference between the groups for gender, age, site, recurrence, symptom (p>0.05). Macrophage colony-stimulating factor (MCSF), CD68, and Ki67 expression was identified in localized and diffuse type TSGCT. But there was no statistically significant difference between the groups for MCSF, CD68, and Ki67 expression (p>0.05).CONCLUSION:
This study shows that although the markers MCSF, CD68, and Ki67 are expressed by localized and diffuse type TSGCT, their lack of specificity limits their use as a subsidiary immunohistochemical marker in the differential diagnosis of localized and diffuse type TSGCTs.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Recidiva
/
Células Gigantes
/
Fator Estimulador de Colônias de Macrófagos
/
Sensibilidade e Especificidade
/
Diagnóstico Diferencial
/
Tumores de Células Gigantes
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Idioma:
Coreano
Revista:
Journal of Korean Orthopaedic Research Society
Ano de publicação:
2013
Tipo de documento:
Artigo
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