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Clinical Implications of Transcranial Magnetic Stimulation in Alzheimer's Dementia / 신경정신의학
Article em Ko | WPRIM | ID: wpr-20871
Biblioteca responsável: WPRO
ABSTRACT
The objective is this study is to provide a comprehensive understanding of the clinical implication of transcranial magnetic stimulation (TMS) in Alzheimer's dementia (AD). We collected studies using TMS in patients with AD and reviewed 41 identified articles. Thirty five articles were about measures of cortical reactivity, plasticity, connectivity, and six articles were about the enhancement of cognitive function in AD. Reduced short-latency afferent inhibition and resting motor threshold which reflect cholinergic dysfunction and enhanced cortical excitability respectively are consistent findings of altered cortical reactivity in AD. In addition, cortical plasticity and connectivity have shown impaired results in AD compared with healthy controls. Repetitively delivered TMS can improve several domains of cognitive function impaired in AD. Although the evidence is still preliminary, TMS has a clinical implication as a diagnostic and therapeutic method in AD. Thorough investigation of factors that can affect the results of TMS and further studies to clarify the results are needed.
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Texto completo: 1 Índice: WPRIM Assunto principal: Plásticos / Demência / Estimulação Magnética Transcraniana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: Ko Revista: Journal of Korean Neuropsychiatric Association Ano de publicação: 2016 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Plásticos / Demência / Estimulação Magnética Transcraniana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: Ko Revista: Journal of Korean Neuropsychiatric Association Ano de publicação: 2016 Tipo de documento: Article