Two Cases of Pseudohypoaldosteronism Type I
Journal of the Korean Pediatric Society
;
: 122-128, 1994.
Artigo
em Coreano
| WPRIM
| ID: wpr-208788
ABSTRACT
Pseudohypoaldosteronism type 1 is a genetic renal tubular disease of salt wasting, presenting in young infants. Tubular unresponsiveness to elevated endogenous and exogenous aldosterone is the suggested pathogenetic mechanism. Oral sodium chloride supplementation relieve the clinical symptoms and electrolyte distrubances. We experienced 2 cases of PHA type 1 in 38-day and 45-day old male infants who were presented with failure to thrive, vomiting and/or dehydration. Laboratory data showed hyponatremia, hyperkalemia, hypochloremia and metabolic acidosis. Renal and adrenal functions were normal. Plasma renin activity and plasma aldosterone concentration were markedly elevated. Under the diagnosis of pseudohypoaldosteronism type 1, oral supplementation of NaCl and/or kayexalate improved the clinical states of the patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plasma
/
Acidose
/
Vômito
/
Pseudo-Hipoaldosteronismo
/
Cloreto de Sódio
/
Renina
/
Desidratação
/
Diagnóstico
/
Aldosterona
/
Insuficiência de Crescimento
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
/
Lactente
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Pediatric Society
Ano de publicação:
1994
Tipo de documento:
Artigo
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