The risk factors and prognosis of methicillin-resistant staphylococcus aureus bacteremia: focus on nosocomial acquisition / 대한내과학회지
Korean Journal of Medicine
;
: 405-414, 2006.
Artigo
em Coreano
| WPRIM
| ID: wpr-208845
ABSTRACT
BACKGROUND:
Staphylococcus aureus is the most common pathogen causing nosocomial infection; it contributes significantly to patient morbidity and mortality. The incidence of S. aureus bacteremia in hospitals as well as communities has significantly increased during the past decade. The purpose of this study was to determine the risk factors and prognosis of methicillin-resistant S. aureus bacteremia.METHODS:
We reviewed the medical records of 164 cases of S. aureus bacteremia during 1999-2003 at the Ewha Womans University MokDong hospital. We retrospectively analyzed the cases, which satisfied the definition of clinically significant bacteremia and whose medical records were available.RESULTS:
The number of methicillin-sensitive Staphylococcus aureus infections (MSSA) was 87 cases and methicillin-resistant Staphylococcus aureus (MRSA) 77 cases. There were 65 cases (84.4%) of nosocomial infection, 9 cases (11.7%) of health-care associated and 3 cases (3.9%) of community-acquired MRSA bacteremia. The risk factors associated with nosocomial MRSA were previous use of antibiotics (OR 15.6, p<0.001) and advanced age (OR 4.9, p=0.017). The risk factor for increased mortality in patients with nosocomial S. aureus bacteremia was septic shock (Hazard ratio 13.2, p<0.001).CONCLUSIONS:
MRSA bacteremia was more frequent in patients with previous antibiotic therapy and advanced age. In addition, the risk factor for mortality in patients with S. aureus bacteremia was septic shock. Additional prospective randomized trials to assess the efficacy and initiation of empirical antibiotics in a well matched cohort study are necessary.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Choque Séptico
/
Staphylococcus aureus
/
Prontuários Médicos
/
Infecção Hospitalar
/
Incidência
/
Estudos Retrospectivos
/
Fatores de Risco
/
Estudos de Coortes
/
Mortalidade
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2006
Tipo de documento:
Artigo
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