A Case of Epidermolysis Bullosa Simplex (Other Generalized Type) / 대한피부과학회지
Korean Journal of Dermatology
;
: 219-222, 2013.
Artigo
em Coreano
| WPRIM
| ID: wpr-208898
ABSTRACT
The other generalized type of epidermolysis bullosa simplex (EBS) is a genetic blistering skin disease, caused by a mutation of the genes encoding keratin 5 and 14. EBS starts at birth and is characterized by generalized blisters following a minor trauma that heals with hyperpigmentation. A 19-year-old man presented with 19-year history of multiple erythematous vesicles in a herpetiform arrangement on the trunk, axilla, and thigh with post-inflammatory hyper-pigmentations. On light and electron microscopy, the biopsy specimen showed intraepidermal blisters that formed within the basal keratinocyte. The serum from a patient with bullous pemphigoid antibody and laminin 5 antibody showed the linear deposition at the floor of the blister on immunofluorescence mapping study. On the basis of our clinical, microscopic, and immunofluorescence findings, we diagnosed the patient as having a generalized type of EBS. Herein, we report on an interesting case of the other generalized type of EBS.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Poliestirenos
/
Dermatopatias
/
Axila
/
Coxa da Perna
/
Biópsia
/
Microscopia Eletrônica
/
Moléculas de Adesão Celular
/
Queratinócitos
/
Epidermólise Bolhosa Simples
/
Imunofluorescência
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
2013
Tipo de documento:
Artigo
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