Relationship between the low-density lipoprotein cholesterol level and clinical outcome after percutaneous coronary intervention in patients with acute myocardial infarction / 대한내과학회지
Korean Journal of Medicine
;
: 692-700, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-209001
ABSTRACT
BACKGROUND/AIMS:
This study examined the relationship between the low-density lipoprotein cholesterol (LDL-C) level and clinical outcome after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).METHODS:
Between January 2006 and December 2007, 867 patients (age, 62.6+/-12.5 years; males, 71%) undergoing a 1-year follow- up after PCI for AMI were divided into five groups according to the LDL-C level or =160 mg/dL.RESULTS:
Smoking (63%), hypertension (46%), and diabetes mellitus (28%) were common risk factors. The history of ischemic heart disease decreased as the LDL-C level increased (p=0.036). Patients with lower LDL-C levels had lower creatinine clearance and higher high-sensitivity C-reactive protein (hsCRP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels. The rate of in-hospital complications after PCI declined with increases in the LDL-C level, except in patients with LDL-C >160 mg/dL (linear p=0.010). There was no correlation between the LDL-C level and the 30-day or 1-year clinical outcome after PCI. After multivariate adjustment, independent predictors of the 1-year mortality after PCI were left ventricular ejection fraction, hsCRP, age, and creatinine clearance.CONCLUSIONS:
Higher LDL-C levels were related to fewer in-hospital complications, but there was no correlation between the LDL-C level and long-term clinical outcome after PCI in Korean patients with AMI.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fumaça
/
Volume Sistólico
/
Proteína C-Reativa
/
Fumar
/
Colesterol
/
Fatores de Risco
/
Isquemia Miocárdica
/
Creatinina
/
Diabetes Mellitus
/
Intervenção Coronária Percutânea
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
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