Sevoflurane Does not Adversely Affect Myocardial Function after Ventricular Septal Defect Repair in Children / 대한마취과학회지
Korean Journal of Anesthesiology
;
: S36-S40, 2007.
Artigo
em Inglês
| WPRIM
| ID: wpr-209756
ABSTRACT
BACKGROUND:
Myocardial dysfunction after cardiopulmonary bypass (CPB) is a significant cause of morbidity and mortality after congenital cardiac surgery. The aim of this study was to evaluate myocardial function on sevoflurane anesthesia after CPB during ventricular septal defect repair.METHODS:
Forty patients were randomly allocated into two groups sevoflurane-fentanyl was used in group S, midazolam-fentanyl in group M. Myocardial performance index (MPI) and ejection fraction (EF) were measured by transesophageal echocardiography before incision and after operation. Serum cardiac Troponin-I (cTnI) levels were measured before incision, and at 0, 12, and 24 h after operation.RESULTS:
MPI increased after operation in both groups (S 0.35 +/- 0.06 vs. 0.43 +/- 0.05, M 0.36 +/- 0.07 vs. 0.46 +/- 0.06 [P < 0.05]), but there was no significant difference between groups. EF decreased after operation in both groups (S 65.1 +/- 5.5% vs. 62.7 +/- 3.9%, M 64.9 +/- 5.3% vs. 61.4 +/- 4.4% ([P < 0.05]), but there was no significant difference between groups. cTnI was markedly elevated after operation, and decreased thereafter. There was no significant difference between groups.CONCLUSIONS:
Both groups showed decreased myocardial function after CPB, but there were no difference between groups. Sevoflurane did not adversely affect intraoperative myocardial function compared to midazolam.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cirurgia Torácica
/
Midazolam
/
Ponte Cardiopulmonar
/
Mortalidade
/
Ecocardiografia Transesofagiana
/
Troponina I
/
Comunicação Interventricular
/
Anestesia
Tipo de estudo:
Estudo prognóstico
Limite:
Criança
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
2007
Tipo de documento:
Artigo
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