Cutaneous Metastasis of Choriocarcinoma / 대한피부과학회지

ABSTRACT

Choriocarcinoma is one of the malignant tumors of trophoblastic cells characterized by secretion of human chorionic gonadotrophin (hCG). Choriocarcinoma often metastasizes to the lung, liver, and brain but skin metastasis is rare. To our knowledge, only one case of cutaneous metastasis was reported in Korea. A 35-year-old female presented with hemoptysis for 1 month. Biopsy from lung nodules revealed metastatic choriocarcinoma. She was subsequently referred to our clinic for evaluation of a rapidly growing, reddish nodule with bleeding tendency on the scalp. Histologic examination demonstrated biphasic pattern of cytotrophoblasts and hCG-positive syncytiotrophoblasts with multiple foci of hemorrhage - typical histologic features of choriocarcinoma. The patient was diagnosed with metastatic choriocarcinoma. We herein report a case of choriocarcinoma with cutaneous metastasis.