Detection of human papillomavirus DNA using the polymerase chain reaction in paraffin-embedded biopsy specimens of condylomata acuminata / 대한피부과학회지
Korean Journal of Dermatology
;
: 508-516, 1993.
Artigo
em Coreano
| WPRIM
| ID: wpr-210740
ABSTRACT
BACKGROUND:
Condylomata acuminata is a sexually transmitted cisease which is caused by the human papillomavirus(HPV). The types of HPV causing condylomata acuminata are HPV 6,11,16,18. HPV 16 and 18 are related to anogenital carcinoma.OBJECTIVE:
The goals of this study were to determine the types cif HPV in condylomata acuminata, and to investigate the relationship between condylomata acuminata and anogenital carcinoma. MEHTODS Polymerase chain reaction and restriction fragment le igth polymorphisms were performed in the paraffin-embedded tissues of 17 cases of condylomata acciminata.RESULTS:
HPV DNA was detected in all of 17 cases of condylomata accuminata tested. HPV 6 and 11 were found in 53% (9/17) and 41% (7/17) of the samples, respectiiely. HPV 16 and/or 18, which are related to anogenital carcinovia, were not detected, except in one case in which HPV 16 was found to be superimposed with HPV 6 and 11.CONCLUSION:
These results suggest that most of condylomata acumirata are caused by HPV 16 and 11, and there is not so much risk of this disease transforming into the aiogenital carcinoma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Biópsia
/
DNA
/
Condiloma Acuminado
/
Reação em Cadeia da Polimerase
/
Papillomavirus Humano 6
/
Papillomavirus Humano 16
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
1993
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS