Methimazole-Induced Bullous Systemic Lupus Erythematosus: A Case Report
Journal of Korean Medical Science
;
: 818-821, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-210921
ABSTRACT
Bullous systemic lupus erythematosus (SLE) is a kind of LE-non-specific bullous skin disease that is rarely induced by a medication. We describe the first case of bullous SLE to develop after administration of methimazole. A 31-yr-old woman presented with generalized erythematous patches, multiple bullae, arthralgia, fever, conjunctivitis, and hemolytic anemia. Biopsy of her bulla showed linear deposition of lgG, lgA, C3, fibrinogen, and C1q at dermo-epidermal junction. She was diagnosed as bullous SLE and treated with prednisolone, dapsone, hydroxychloroquine, and methotrexate. Our experience suggests that SLE should be considered as a differential diagnosis when bullous skin lesions develop in patients being treated for hyperthyroidism.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pele
/
Antitireóideos
/
Nefrite Lúpica
/
Prednisolona
/
Doença de Graves
/
Vesícula
/
Antirreumáticos
/
Quimioterapia Combinada
/
Hidroxicloroquina
/
Imunossupressores
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2012
Tipo de documento:
Artigo
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