Mixed Exocrine and Endocrine Carcinoma in the Stomach: A Case Report
Journal of Gastric Cancer
;
: 122-125, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-211529
ABSTRACT
We report a rare case of the coexistence of a gastric small cell neuroendocrine carcinoma with a gastric adenocarcinoma. A 62-year-old man presented with epigastric soreness for 1 month. Esophagogastroduodenoscopy revealed a Borrmann type I tumor at the lesser curvature of the lower body of the stomach. The patient underwent a distal gastrectomy with D2 lymph node dissection and the resected specimen exhibited a 3.5x3.5 cm sized, fungating lesion. Two separated, not intermingling, lesions with non-adenocarcinoma components encircled by well differentiated adenocarcinoma components were identified microscopically. The non-adenocarcinoma component showed neuroendocrine features, such as a solid and trabecular pattern, and the tumor cells showed a high nuclear grade with minimal cytoplasm, indistinct nucleoli, and positive response for synaptophysin, CD56. The final pathological diagnosis was a gastric mixed exocrine-endocrine carcinoma (MEEC) composed of an adenocarcinoma and small cell neuroendocrine carcinoma of the collision type.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Estômago
/
Neoplasias Gástricas
/
Adenocarcinoma
/
Endoscopia do Sistema Digestório
/
Sinaptofisina
/
Tumores Neuroendócrinos
/
Carcinoma Neuroendócrino
/
Citoplasma
/
Gastrectomia
/
Excisão de Linfonodo
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Gastric Cancer
Ano de publicação:
2011
Tipo de documento:
Artigo
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