Case Report of Occupational Asthma Induced by Polyvinyl Chloride and Nickel
Journal of Korean Medical Science
;
: 1540-1542, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-212591
ABSTRACT
Polyvinyl chloride (PVC) is a widely used chemical for production of plastics. However occupational asthma (OA) caused by PVC has been reported only rarely. We report a 34-yr-old male wallpaper factory worker with OA due to PVC and nickel (Ni) whose job was mixing PVC with plasticizers. He visited the emergency room due to an asthma attack with moderate airflow obstruction and markedly increased sputum eosinophil numbers. A methacholine challenge test was positive (PC20 2.5 mg/mL). Bronchoprovocation tests with both PVC and Ni showed early and late asthmatic responses, respectively. Moreover, the fractional concentration of exhaled nitric oxide (FeNO) was increased after challenge with PVC. To our knowledge, this is the first case of OA in Korea induced by exposure to both PVC and Ni. We suggest that eosinophilic inflammation may be involved in the pathogenesis of PVC-induced OA and that FeNO monitoring can be used for its diagnosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plastificantes
/
Cloreto de Polivinila
/
Testes Respiratórios
/
Testes de Provocação Brônquica
/
Exposição Ocupacional
/
Expiração
/
Exposição Ambiental
/
Eosinofilia
/
Asma Ocupacional
/
Contagem de Leucócitos
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2013
Tipo de documento:
Artigo
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