A Case of Hepatomegaly due to Diabetic Glycogenosis Reversed by Glycemic Control / 대한내분비학회지
Journal of Korean Society of Endocrinology
;
: 223-228, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-21311
ABSTRACT
Diabetes mellitus is well known to be associated with various structural and functional liver abnormalities. If diabetic patients are accompanied by hepatomegaly or abnormal findings from a liver function test, the most common pathological findings are steatosis and glycogenosis. The steatosis is characterized by deposition of macrovesicular fat droplets in the hepatocytes, which is common in obese, type 2 diabetes mellitus. If macrovesicular steatosis is combined with mixed inflammatory infiltrate, without evidence of alcoholic hepatitis, the case could be diagnosed as nonalcoholic steatohepatitis (NASH). NASH has the possibility of progressing to cirrhosis. Secondary glycogenosis is common in uncontrolled type 1 diabetes mellitus, and is completely reversible. A 22-year-old male, with uncontrolled type 1 diabetes mellitus, was admitted with anorexia, nausea and right upper quadrant pain. Hepatomegaly and elevated aminotransferases were noted. He was diagnosed as diabetic glycogenosis using computed tomogram and liver biopsy. The hepato megaly and liver function test abnormalities were markedly improved with glycemic control
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Biópsia
/
Fibrose
/
Anorexia
/
Doença de Depósito de Glicogênio
/
Hepatócitos
/
Diabetes Mellitus
/
Diabetes Mellitus Tipo 1
/
Diabetes Mellitus Tipo 2
/
Fígado Gorduroso
/
Transaminases
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of Korean Society of Endocrinology
Ano de publicação:
2004
Tipo de documento:
Artigo
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