The Influence of Anticoagulants and Time of Measurements on D-Dimer Determinations / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 7-10, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-213943
ABSTRACT
BACKGROUND:
We evaluated the effects of anticoagulants used in blood sampling and time of mesurements after blood collection on D-dimer determinations.METHODS:
A total of 32 samples of sodium citrated plasma, and 23 samples each of serum and ethylene diamine tetraacetic acid (EDTA) plasma, were studied. D-dimer was measured by enzyme linked fluorescent assay using a VIDAS analyzer.RESULTS:
The mean+/-SD (median) of D-dimer titers in citrated plasma, serum, and EDTA plasma samples immediately after blood collection were 282.7+/-201.1 (224.6) microgram/L, 255.1+/-206.8 (197.3) microgram/L, and 313.3+/-230.8 (246.4) microgram/L respectively. The results obtained for the three different sample groups were well correlated. While the upper limit of the reference range for D-dimer for citrated plasma has been set at 500 microgram/L, the cut-off values for serum and EDTA plasma were 400 microgram/L (100%sensitivity and specificity), and 585 microgram/L (100% sensitivity and 94.7% specificity), respectivelyCONCLUSIONS:
In addition to citrated plasma, both serum and EDTA plasma can be used for D-dimer assay. A delay in the time of measurements after blood collection does not influence the results significantly.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plasma
/
Valores de Referência
/
Sódio
/
Ácido Edético
/
Anticoagulantes
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2004
Tipo de documento:
Artigo
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