Impact of Post-Stroke Cognitive Impairment with No Dementia on Health-Related Quality of Life / 대한뇌졸중학회지
Journal of Stroke
;
: 49-56, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-214098
ABSTRACT
BACKGROUND AND PURPOSE:
Health-related quality of life (HRQoL) is a multidimensional concept that signifies a subjective evaluation of perceived health; hence, it has gained wide acceptance in geriatrics. However, its application has not been tested in patients with post-stroke cognitive impairment with no dementia (PSCIND). We investigated whether PSCIND interferes with HRQoL measured by EQ-5D, compared the findings to those of healthy people with normal cognition, and evaluated the influence of each cognitive domain on this score.METHODS:
In total, 1,528 subjects were identified who had undergone neuropsychological assessment using the 60-min protocol of the Korean version of Vascular Cognitive Impairment Harmonization Standards, EQ-5D, and magnetic resonance imaging at the stroke prevention clinic. Fifty PSCIND patients were matched to 50 post-stroke dementia (PSD) patients and 50 normal age- (+/-3 years) and sex-matched controls. The effects of PSCIND, PSD, and control groups upon the EQ-5Dindex score were tested by generalized estimating equation modeling.RESULTS:
Estimated means+/-standard errors of EQ-5Dindex scores were as follows 0.94+/-0.06 (control group), 0.86+/-0.08 (PSCIND group), and 0.61+/-0.32 (PSD group); and the difference among the three groups was statistically significant (P<0.0001). Pairwise comparisons showed that EQ-5Dindex scores in the PSCIND group differed from those in the PSD and control groups (both P<0.01). No cognitive domain was specifically associated with EQ-5Dindex scores after adjusting for functional status.CONCLUSIONS:
This study shows that PSCIND may interfere with the quality of life in stroke victims.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Qualidade de Vida
/
Imageamento por Ressonância Magnética
/
Cognição
/
Acidente Vascular Cerebral
/
Demência
/
Geriatria
Tipo de estudo:
Guia de Prática Clínica
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Stroke
Ano de publicação:
2013
Tipo de documento:
Artigo
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