Clinicopathologic Characteristics and Treatment Outcomes of Penile Cancer
The World Journal of Men's Health
;
: 28-33, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-214132
ABSTRACT
PURPOSE:
The aim of this study was to assess the clinicopathologic characteristics of penile cancer, including patterns of therapy, oncologic results, and survival. MATERIALS ANDMETHODS:
Between January 2005 and July 2015, 71 patients at 6 institutions who had undergone penectomy or penile biopsy were enrolled. Their medical records were reviewed to identify the mode of therapy, pathology reports, and cancer-specific survival (CSS) rate.RESULTS:
Clinicopathologic and outcome information was available for 52 male patients (mean age, 64.3 years; mean follow-up, 61.4 months). At presentation, 17 patients were node-positive, and 4 had metastatic disease. Management was partial penectomy in 34 patients, total penectomy in 12 patients, and chemotherapy or radiotherapy in 6 patients. The pathology reports were squamous cell carcinoma in 50 patients and other types of carcinoma in the remaining 2 patients. Kaplan-Meier survival analysis showed a 5-year CSS rate of 84.0%. In univariate and multivariate analyses, the American Joint Committee on Cancer (AJCC) stage and pathologic grade were associated with survival.CONCLUSIONS:
Partial penectomy was the most common treatment of penile lesions. The oncologic outcomes were good, with a 5-year CSS of 84.0%. The AJCC stage and pathologic grade were independent prognostic factors for survival.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Neoplasias Penianas
/
Prognóstico
/
Radioterapia
/
Biópsia
/
Carcinoma de Células Escamosas
/
Prontuários Médicos
/
Análise Multivariada
/
Seguimentos
/
Resultado do Tratamento
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
The World Journal of Men's Health
Ano de publicação:
2017
Tipo de documento:
Artigo
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