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Clinical Manifestations of Intraocular Lymphoma
Journal of the Korean Ophthalmological Society ; : 78-84, 2009.
Artigo em Coreano | WPRIM | ID: wpr-215273
ABSTRACT

PURPOSE:

To investigate the clinical features and prognosis of primary intraocular lymphoma (PIOL).

METHODS:

A retrospective review of medical records was performed in 9 patients who were diagnosed and treated as PIOL in the Department of Ophthalmology, Seoul National University Hospital.

RESULTS:

Among patients who were enrolled in the study, 14 eyes were examined. Thirteen eyes (92.9%) showed yellowish subretinal or choroidal infiltrates which is a characteristic finding of PIOL in fundus examination and fluorescein angiography. Three patients presented with ocular symptoms initially, and 5 patients later presented with central nerve system (CNS) involvement. Only 1 patient showed PIOL without CNS involvement. Among 6 patients (9 eyes) that received systemic chemotherapy or ocular irradiation, 5 patients (7 eyes, 77.8%) responded. Among those patients, 3 patients (4 eyes) showed relapse of PIOL. Five patients died during the mean follow-up period of 43.3 months, and the median survival time was 47 months.

CONCLUSIONS:

The most common characteristic fundus finding of PIOL is subretinal or choroidal infiltration. Ocular irradiation combined with systemic chemotherapy is the first method of treatment, although long-term prognosis is poor.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Oftalmologia / Prognóstico / Recidiva / Angiofluoresceinografia / Prontuários Médicos / Estudos Retrospectivos / Seguimentos / Corioide / Olho / Linfoma Tipo de estudo: Estudo observacional / Estudo prognóstico Limite: Humanos Idioma: Coreano Revista: Journal of the Korean Ophthalmological Society Ano de publicação: 2009 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Oftalmologia / Prognóstico / Recidiva / Angiofluoresceinografia / Prontuários Médicos / Estudos Retrospectivos / Seguimentos / Corioide / Olho / Linfoma Tipo de estudo: Estudo observacional / Estudo prognóstico Limite: Humanos Idioma: Coreano Revista: Journal of the Korean Ophthalmological Society Ano de publicação: 2009 Tipo de documento: Artigo