Clinical Manifestations of Intraocular Lymphoma
Journal of the Korean Ophthalmological Society
;
: 78-84, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-215273
ABSTRACT
PURPOSE:
To investigate the clinical features and prognosis of primary intraocular lymphoma (PIOL).METHODS:
A retrospective review of medical records was performed in 9 patients who were diagnosed and treated as PIOL in the Department of Ophthalmology, Seoul National University Hospital.RESULTS:
Among patients who were enrolled in the study, 14 eyes were examined. Thirteen eyes (92.9%) showed yellowish subretinal or choroidal infiltrates which is a characteristic finding of PIOL in fundus examination and fluorescein angiography. Three patients presented with ocular symptoms initially, and 5 patients later presented with central nerve system (CNS) involvement. Only 1 patient showed PIOL without CNS involvement. Among 6 patients (9 eyes) that received systemic chemotherapy or ocular irradiation, 5 patients (7 eyes, 77.8%) responded. Among those patients, 3 patients (4 eyes) showed relapse of PIOL. Five patients died during the mean follow-up period of 43.3 months, and the median survival time was 47 months.CONCLUSIONS:
The most common characteristic fundus finding of PIOL is subretinal or choroidal infiltration. Ocular irradiation combined with systemic chemotherapy is the first method of treatment, although long-term prognosis is poor.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oftalmologia
/
Prognóstico
/
Recidiva
/
Angiofluoresceinografia
/
Prontuários Médicos
/
Estudos Retrospectivos
/
Seguimentos
/
Corioide
/
Olho
/
Linfoma
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2009
Tipo de documento:
Artigo
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