Connecting Myokines and Metabolism
Endocrinology and Metabolism
;
: 235-245, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-215491
ABSTRACT
Skeletal muscle is the largest organ of the body in non-obese individuals and is now considered to be an endocrine organ. Hormones (myokines) secreted by skeletal muscle mediate communications between muscle and liver, adipose tissue, brain, and other organs. Myokines affect muscle mass and myofiber switching, and have profound effects on glucose and lipid metabolism and inflammation, thus contributing to energy homeostasis and the pathogenesis of obesity, diabetes, and other diseases. In this review, we summarize recent findings on the biology of myokines and provide an assessment of their potential as therapeutic targets.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Biologia
/
Encéfalo
/
Tecido Adiposo
/
Músculo Esquelético
/
Metabolismo dos Lipídeos
/
Glucose
/
Homeostase
/
Inflamação
/
Fígado
/
Metabolismo
Idioma:
Inglês
Revista:
Endocrinology and Metabolism
Ano de publicação:
2015
Tipo de documento:
Artigo
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