A Case of 5-fluorouracil-induced Phototoxicity / 대한피부과학회지
Korean Journal of Dermatology
;
: 1364-1366, 2006.
Artigo
em Coreano
| WPRIM
| ID: wpr-215676
ABSTRACT
5-fluorouracil (5-FU) is an antimetabolite which prevents thymine synthesis and suppresses the utilization of preformed uracil. A variety of cutaneous reactions have been reported with the use of systemic 5-FU, the most common being photosensitivity. We report a case of 5-FU induced phototoxicity in a 73-year-old male. The patient had tender and slightly pruritic scaly and crusted erythema on sun-exposed areas. A biopsy revealed necrotic keratinocytes with epidermal degeneration. After the cessation of 5-FU, the skin lesions showed a marked improvement, and there was no further photosensitivity to the skin.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pele
/
Timina
/
Uracila
/
Biópsia
/
Queratinócitos
/
Dermatite Fototóxica
/
Eritema
/
Fluoruracila
Limite:
Idoso
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
2006
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS