Association between Tuberculin Responses and Serum IgE
Journal of the Korean Pediatric Society
;
: 502-505, 2000.
Artigo
em Coreano
| WPRIM
| ID: wpr-216071
ABSTRACT
PURPOSE:
Atopy is a state of allergic response, mediated by IgE, to common environmental allergens. In recent decades, there has been an increase in prevalence of atopic disorders in children in developed countries. The factor associated with the rise of atopy incidence may be declining exposure to some infection opportunities. The aim of this study is to determine if the immune response to Mycobacterium tuberculosis can suppress atopy by investigating the association between tuberculin responses and serum IgE.METHODS:
We divided the patients into two groups according to tuberculin skin test. Group A showed positive response (induration diameter > or =10mm), while Group B showed negative response (induration diameter< l0mm). A comparison was made between the two groups in terms of age, sex, serum total IgE and allergen-specific IgE.RESULTS:
Twenty-one patients comprised Group A and 72 comprised Group B. The mean serum total IgE concentration and the number of patients showing positive MAST in Group B was significantly higher than that of Group A (P<0.05).CONCLUSION:
In our study, there was an inverse association between delayed hypersensitivity to Mycobacterium tuberculosis and atopy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tuberculina
/
Imunoglobulina E
/
Testes Cutâneos
/
Alérgenos
/
Países Desenvolvidos
/
Incidência
/
Prevalência
/
Hipersensibilidade Tardia
/
Mycobacterium tuberculosis
Tipo de estudo:
Estudo de incidência
/
Estudo de prevalência
/
Estudo prognóstico
Limite:
Criança
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Pediatric Society
Ano de publicação:
2000
Tipo de documento:
Artigo
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