A Database of Gene Expression Profiles of Korean Cancer Genome
Genomics & Informatics
;
: 86-89, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-216093
ABSTRACT
Because there are clear molecular differences entailing different treatment effectiveness between Korean and non-Korean cancer patients, identifying distinct molecular characteristics of Korean cancers is profoundly important. Here, we report a web-based data repository, namely Korean Cancer Genome Database (KCGD), for searching gene signatures associated with Korean cancer patients. Currently, a total of 1,403 cancer genomics data were collected, processed and stored in our repository, an ever-growing database. We incorporated most widely used statistical survival analysis methods including the Cox proportional hazard model, log-rank test and Kaplan-Meier plot to provide instant significance estimation for searched molecules. As an initial repository with the aim of Korean-specific marker detection, KCGD would be a promising web application for users without bioinformatics expertise to identify significant factors associated with cancer in Korean.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Biomarcadores
/
Expressão Gênica
/
Modelos de Riscos Proporcionais
/
Resultado do Tratamento
/
Genoma
/
Biologia Computacional
/
Genômica
/
Transcriptoma
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Genomics & Informatics
Ano de publicação:
2015
Tipo de documento:
Artigo
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