Imaging evaluation of non-alcoholic fatty liver disease: focused on quantification
Clinical and Molecular Hepatology
;
: 290-301, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-216537
ABSTRACT
Non-alcoholic fatty liver disease (NAFLD) has been an emerging major health problem, and the most common cause of chronic liver disease in Western countries. Traditionally, liver biopsy has been gold standard method for quantification of hepatic steatosis. However, its invasive nature with potential complication as well as measurement variability are major problem. Thus, various imaging studies have been used for evaluation of hepatic steatosis. Ultrasonography provides fairly good accuracy to detect moderate-to-severe degree hepatic steatosis, but limited accuracy for mild steatosis. Operator-dependency and subjective/qualitative nature of examination are another major drawbacks of ultrasonography. Computed tomography can be considered as an unsuitable imaging modality for evaluation of NAFLD due to potential risk of radiation exposure and limited accuracy in detecting mild steatosis. Both magnetic resonance spectroscopy and magnetic resonance imaging using chemical shift technique provide highly accurate and reproducible diagnostic performance for evaluating NAFLD, and therefore, have been used in many clinical trials as a non-invasive reference of standard method.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Biópsia
/
Imageamento por Ressonância Magnética
/
Espectroscopia de Ressonância Magnética
/
Ultrassonografia
/
Exposição à Radiação
/
Hepatopatia Gordurosa não Alcoólica
/
Fígado
/
Hepatopatias
/
Métodos
Tipo de estudo:
Estudo diagnóstico
/
Pesquisa qualitativa
Idioma:
Inglês
Revista:
Clinical and Molecular Hepatology
Ano de publicação:
2017
Tipo de documento:
Artigo
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