Tacrolimus-induced, Transplant-associated Thrombotic Microangiopathies after Lung Transplantation / 대한이식학회지
The Journal of the Korean Society for Transplantation
;
: 94-97, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-219372
ABSTRACT
We report a case of tacrolimus-induced transplant-associated thrombotic microangiopathies (TA-TMA) after lung transplantation. A 71-year-old man underwent lung transplantation secondary to idiopathic pulmonary fibrosis. After 4 months, he presented with abdominal discomfort and dyspnea, and was diagnosed with hemolytic anemia and thrombocytopenia. Tacrolimus was considered the cause of the TMA. Tacrolimus was stopped and several sessions of plasma exchange were performed immediately after diagnosis of TA-TMA. However, his platelet count did not normalize, gastrointestinal bleeding was recurrent, and severe pneumonia developed, following which he died. TA-TMA are rare but severe, life-threatening complications in lung transplant recipients. Therefore, the possibility of TA-TMA should be considered in posttransplant recipients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Troca Plasmática
/
Contagem de Plaquetas
/
Pneumonia
/
Trombocitopenia
/
Transplante de Pulmão
/
Tacrolimo
/
Diagnóstico
/
Dispneia
/
Fibrose Pulmonar Idiopática
/
Microangiopatias Trombóticas
Tipo de estudo:
Estudo diagnóstico
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
The Journal of the Korean Society for Transplantation
Ano de publicação:
2016
Tipo de documento:
Artigo
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