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Hydatidiform Mole with a Coexisting Fetus: Report of three cases with nuclear DNA ploidy analysis by flow cytometry or chromosomal analysis
Korean Journal of Pathology ; : 348-354, 1992.
Artigo em Coreano | WPRIM | ID: wpr-219882
ABSTRACT
Three cases of hydatidiform mole with a coexisting fetus are described. In two cases, flow cytometric analysis of nuclear DNA content from paraffin-embedded, molar tissues and normal-appearing placental tissues showed diploid pattern. One case had karyotypes of 46, XX both in fetal skin fibroblasts and in molar tissues. Microscopically, the villi showed diffuse hydropic swelling with circumferential trophoblastic proliferations and consistent with the diagnosis of complete mole. Two patient had persistent gestational trophoblastic neoplasia on the follow-up. Therefore, in cases of hydatidiform mole with a coexisting fetus, dizygotic twin pregnancies composed of a normal pregnancy from one ovum and a complete mole pregnancy from the other ovum must be considered and the patients should be followed with serum beta-hCG measurements.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Limite: Feminino / Humanos / Gravidez Idioma: Coreano Revista: Korean Journal of Pathology Ano de publicação: 1992 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Limite: Feminino / Humanos / Gravidez Idioma: Coreano Revista: Korean Journal of Pathology Ano de publicação: 1992 Tipo de documento: Artigo