Vitreous Seeding Associated with Melanocytoma of the Optic Disc

ABSTRACT

Melanocytoma is defined as a specific variant of nevus, located on the optic disc or anywhere in the uveal tract, characterized clinically by a dark brown to black color, and composed histopathologically of deeply pigmented, plump, round to polyhedral nevus cells with small, round, uniform nuclei. The case of a 52-year-old woman with presumed melanocytoma of the left optic disc associated with vitreous seeding is presented. Fluorescein angiography, perimetry, magnetic resonance imaging and bone scan were performed. These findings are consistent with melanocytoma of the optic disc. No interval change of the tumor during the following periods was observed. The possible mechanisms responsible for this vitreoua seeding of melanocytoma of the optic disc are disscuased.